Stem Cell Factor Receptor

《英文msh詞典》Stem Cell Factor Receptor
[同義詞] Stem Cell Factor Receptor
[主題詞] Proto-Oncogene Protein c-kit
[中文釋義] 干細胞因子受體
[英文釋義] A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic,gonadal,and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEIN C-KIT are associated with PIEBALDISM,while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis.